The award will be presented to the senior author of the most impactful study published in Alzheimer's research over the preceding two years. The purpose of the award is to highlight the tremendous work being done in Alzheimer's research today and to honor the pioneering work of Dr. Inge Grundke-Iqbal.

Eligibility Criteria
  • The award will be given to the senior author(s)* of the most impactful study on the biology of Alzheimer's disease and related conditions published during the two calendar years preceding the next Alzheimer's Association International Conference® (AAIC®). The publication period for AAIC 2025 is January 1, 2023 – December 31, 2024.
  • The recipient(s) must be able to present a 25-minute plenary presentation at AAIC 2025 (July 27 - 31, 2025, Toronto, Canada and online) to receive the award unless otherwise unable to do so because of health restrictions or other serious conflicts.
  • Nominees must demonstrate a current or past affiliation to a major academic or research/treatment institution(s).
  • The award will be presented to an individual investigator(s). Institutions or organizations are not eligible to receive the award.
  • Nominations may be made on behalf of individuals who are living at the time of the nomination.
  • There are no restrictions with regard to race, gender, nationality, geographic location, or religious or political views.
  • Self-nominations are not accepted.
  • Members of the AAIC Scientific Program Committee are not eligible for consideration.
Past Recipients
  • 2014: Kári Stefánsson, M.D., Dr. Med.“A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline”
  • 2015: Li Gan, Ph.D.“Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models”
  • 2016: Tsuneya Ikezu, M.D., Ph.D.“Depletion of microglia and inhibition of exosome synthesis halt tau propagation”
  • 2017: Ben Barres, M.D., Ph.D. "Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes"
  • 2018: Robert Tycko, Ph.D."Structural variation in amyloid-β fibrils from Alzheimer’s disease clinical subtypes”
  • 2019: Shane Liddelow, Ph.D.“Neurotoxic reactive astrocytes are induced by activated microglia”
  • 2020: Yakeel T. Quiroz, Ph.D. "Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report"
  • 2021: Fernanda De Felice, Ph.D. "Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models"
  • 2022: Rakez Kayed, Ph.D."Tau Oligomer Induced HMGB1 Release Contributes to Cellular Senescence and Neuropathology Linked to Alzheimer’s Disease and Frontotemporal Dementia"
  • 2023: Cristian Lasagna-Reeves, Ph.D. "Bassoon Contributes to Tau-Seed Propagation and Neurotoxicity"
  • 2024: Tara Spires-Jones, DPhil. “Synaptic oligomeric tau in

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* Nominee's Information: 

Note, we are seeking nominations of the senior author of the study, regardless of the order of authorship on the publication. 

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* Nominee's Organization/Institution:

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* Publication Details

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* Publication Month/Year:

Note the eligible publication period for AAIC 2025: Jan 1, 2023, through Dec 31, 2024

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* Publication:

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* Briefly describe the impact of the study on the field (50 - 200 words):

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* Nominator's Information 

Nomination Submitted by:

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* Nominator's Email Address:

This email address will only be used to contact the Nominator regarding this Inge Grundke-Iqbal nomination. This does not update the Nominator's email preferences to ISTAART or the Alzheimer's Association. To update the general email opt-in/out subscription, please contact ISTAART.

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